This 2-part special issue features 14 review articles with an attempt to cover IHC automation, standardization of diagnostic IHC, and the role of IHC in diagnosing tumors in major organs and tumors of unknown primary. This series begins with an article emphasizing standardization of diagnostic IHC in the preanalytic, analytic, and postanalytic phases, with a specific focus on (1) newly proposed guidelines on antibody validation from the College of American Pathologists Pathology and Laboratory Quality Center, (2) testing/optimizing a new antibody and troubleshooting, (3) interpreting and reporting IHC assay results, (4) continuing quality improvement programs, and (5) developing and implementing the concept of best practices in IHC.
from Fan Lin (2014) Evolving Practices of Diagnostic Immunohistochemistry. Archives of Pathology & Laboratory Medicine: December 2014, Vol. 138, No. 12, pp. 1561-1563.
Overview of Automated Immunohistochemistry
Immunohistochemistry in Undifferentiated Neoplasm/Tumor of Uncertain Origin
Utility of Immunohistochemistry in the Diagnosis of Pleuropulmonary and Mediastinal Cancers: A Review and Update
Application of Immunohistochemistry in Breast Pathology: A Review and Update
The Application of Immunohistochemical Biomarkers in Urologic Surgical Pathology
New Immunohistochemistry for B-Cell Lymphoma and Hodgkin Lymphoma
Utility of Immunohistochemistry in the Pancreatobiliary Tract
The Utility of Immunohistochemistry in the Differential Diagnosis of Gynecologic Disorders
Review and Updates of Immunohistochemistry in Selected Salivary Gland and Head and Neck Tumors
Application of Immunohistochemistry in Thyroid Pathology
Immunohistochemistry in Dermatopathology
An Update on the Application of Newly Described Immunohistochemical Markers in Soft Tissue Pathology
